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MYP_080428
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Basic Information
Ocellatin-P1 (Pentadactylin)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
25 amino acids
C112H200N30O34S
Standard
Sequence
GLLDTLKGAAKNVVGSLASKVMEKL
Physicochemical Analysis
2543.03 Da
9.53
1.76
1.55
0.0704
0.37
0.53
0.15
-16.79
124.80
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1044.18
-9.96
36.0
37.0
91.0
177.0
0.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0199267 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus pentadactylus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Streptococcus Group B HNTCC 80130
50 μM
MIC
PaperPentadactylin: an antimicrobial peptide from the skin secretions of the South American bullfrog Leptodactylus pentadactylus PMID16236555
RECORD: Rec_0219615 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus pentadactylus [Animal]
Pentadactylin
Structure & Mods
ribosomal mature linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic Cytolytic
Erythrocytes
400.0 μM
HC50
PaperJ.D. King et al. / Comparative Biochemistry and Physiology, Part C 141 (2005) 393-397. Pentadactylin: an antimicrobial peptide from the skin secretions of the South American bullfrog Leptodactylus pentadactylus PMID16236555
RECORD: Rec_0229891 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus pentadactylus [Animal]
Frog skin active peptide (FSAP); Ocellatin subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Anti-Gram-positive Hemolytic
Streptococcus
PMID16236555 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16236555/
RECORD: Rec_0232017 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Toxic Antimicrobial Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0234989 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus pentadactylus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Streptococcus Group B HNTCC 80130
50 μM
MIC
PMID16236555 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16236555/
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