Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length196 amino acids

Chemical FormulaC986H1563N269O266S9

DescriptionStandard

        PKTLPMAHEPMLLLAVTELVANSAAFTYFTAGALRRNFSSDMLPRQFPLQLRTKSMEVFSPQLQERYPDQPMELHLWARQQPLISCHPDALHGTLFSSAEAFVVLPNATRVPAFLLNIDANVTGKPTITRNRLGGTVRLTGLVPDPELAWTPLPVLCQAQGRPVPQVKRLETLLKFGLWLFGVPRVNSKCSPCPAP
    

Molecular Weight21730.19 Da

Isoelectric Point (pI)9.51

Net Charge (pH 7.0)6.29

Net Charge (pH 7.4) 5.94

Charge Density (pH 7.0) 0.0321

GRAVY Index-0.01

Hydrophobic Moment 0.59

Boman Index0.08

Instability Index51.63

Aliphatic Index 93.06

Aromaticity 0.0765

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8396.77

LogP -102.98

H-bond Donors 287.0

H-bond Acceptors 285.0

Rotatable Bonds 682.0

Heavy Atoms 1530.0

Ring Count 45.0

Amide Bonds 212.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0384681 VERIFIED: NO

Provenance & Taxonomy

OrganismSinosuthora webbiana [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria