Peptide Database

Peptide NameP7G/P8G/P12G/P16G/P24G-pleurain-E1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length26 amino acids

Chemical FormulaC117H196N38O29S

DescriptionStandard

        AKAWGIGGHVIGQIVGVRIRGLCGNV
    

Molecular Weight2631.11 Da

Isoelectric Point (pI)10.86

Net Charge (pH 7.0)2.87

Net Charge (pH 7.4) 2.62

Charge Density (pH 7.0) 0.1105

GRAVY Index0.69

Hydrophobic Moment 0.34

Boman Index0.31

Instability Index-5.95

Aliphatic Index 127.31

Aromaticity 0.0385

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1071.29

LogP -9.75

H-bond Donors 39.0

H-bond Acceptors 34.0

Rotatable Bonds 87.0

Heavy Atoms 185.0

Ring Count 3.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0040041 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus

Activity12.6 μg/mL

MethodMIC

RECORD: Rec_0056242 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli

Activity25 μg/mL

MethodMIC

RECORD: Rec_0294089 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetCandida albicans

Activity50 μg/mL

MethodMIC