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MYP_080241
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Basic Information
Secretin Human
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Gastrointestinal bioactivity
Hormonal / Endocrine ▸ Hormone peptide
Metabolic
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
27 amino acids
C130H219N43O41
Standard
Sequence
HSDGTFTSELSRLREGARLQRLLQGLV
Physicochemical Analysis
3040.39 Da
9.45
0.85
0.60
0.0316
-0.45
0.76
-0.17
53.46
101.11
0.0370
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1395.43
-16.41
51.0
43.0
105.0
214.0
2.0
28.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0243003 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
Enzyme
32630
Structure & Mods
single-chain therapeutic peptide/protein [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone replacement Diagnostic
0.75 hours
RECORD: Rec_0284690 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
Enzyme
9606
Structure & Mods
single-chain therapeutic peptide/protein [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone replacement Diagnostic
0.75 hours
RECORD: Rec_0402961 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Secretin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone Endocrine Growth regulation Development regulation Receptor modulation ACE inhibitory
Mammalian: 3.5 hour; Yeast: 10 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Secretin (Homo sapiens): PMID 25332973 PMID25332973 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25332973/
RECORD: Rec_0413198 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone
bicarbonate secretion
RECORD: Rec_0423195 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cell-Cell Communication
PaperNeuroPedia: neuropeptide database and spectral library (https://pubmed.ncbi.nlm.nih.gov/21821666/) PMID21821666 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21821666/
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