Peptide Database

Peptide NameCircularin A uberolysin family circular bacteriocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length99 amino acids

Chemical FormulaC451H758N116O125S2

DescriptionStandard

        MKIKKVLAGTLGLGVVGFVLALDQFSGGGLANLTLQYDISAVNAGRIVTAIEWASDMSAVISLAGAILGAGIGAAAISAAIAIAKKKLLKEGKKAAVLY
    

Molecular Weight9869.67 Da

Isoelectric Point (pI)9.76

Net Charge (pH 7.0)4.50

Net Charge (pH 7.4) 4.26

Charge Density (pH 7.0) 0.0454

GRAVY Index0.88

Hydrophobic Moment 0.71

Boman Index0.36

Instability Index12.33

Aliphatic Index 134.24

Aromaticity 0.0505

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3808.38

LogP -31.61

H-bond Donors 133.0

H-bond Acceptors 132.0

Rotatable Bonds 338.0

Heavy Atoms 694.0

Ring Count 6.0

Amide Bonds 102.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0100433 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus thuringiensis serovar guiyangiensis [Bacterium]

FamilyCircular bacteriocin

Structure & Mods

Configcyclic peptide topology reported [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Non-hemolytic Non-ribosomal