Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length434 amino acids

Chemical FormulaC2252H3488N576O601S13

DescriptionStandard

        LFYFILFYFILFYFILFYFILFYFLYVRLNLRNFQLPHSQISLVPNEGLQVSISNAFAELDGNWRVKLRFLRQRGSFNLKLSHVYIKTILKLGRDASGKPTVDISACSTSISNVRVRFSGKLSWLYNLFRRTIESKLKKNLEGKVCGSLSSSVRRFLQPYLQTVPVTAKIDTTVGIDYSLTAPPVATAQFLNADLKGECFSLAQHTAIPFTPPALAFPPDHSRMVYFGVSSYFFNTASFAYHTAGALVFEITDSMIPKDIEFRLNTSTFAAFLPQLDEMYPNMPMKFRLSTPSAPFLSIGPDGVSLQPVVDIQAYAIYPNGSLAPLFLLSLTGNVSATADVRSGRMVGSLALGRMKLTLKHSDVGTGTFKVKMMQSIMNIVASSVLLPRLNERLGKGFPLPLPAQVQLSDLLVQFHENFLLFGANVHYQPRQGR
    

Molecular Weight48664.13 Da

Isoelectric Point (pI)9.77

Net Charge (pH 7.0)17.44

Net Charge (pH 7.4) 16.70

Charge Density (pH 7.0) 0.0402

GRAVY Index0.20

Hydrophobic Moment 0.78

Boman Index0.15

Instability Index39.14

Aliphatic Index 98.62

Aromaticity 0.1290

Extinction Coeff. Reduced 36330.00

Extinction Coeff. Oxidized 36455.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0187302 VERIFIED: NO

Provenance & Taxonomy

OrganismAnser cygnoid [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria