Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length69 amino acids

Chemical FormulaC356H567N97O107S10

DescriptionStandard

        MRIFDYLHSLCYVTFILPATCTLVDADRCTKRYGRCKRDCLEIEKQIDICSSPRKICCTERLYEEDDMF
    

Molecular Weight8238.55 Da

Isoelectric Point (pI)5.72

Net Charge (pH 7.0)-1.48

Net Charge (pH 7.4) -1.89

Charge Density (pH 7.0) -0.0214

GRAVY Index-0.24

Hydrophobic Moment 0.81

Boman Index-0.13

Instability Index67.71

Aliphatic Index 79.13

Aromaticity 0.1014

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6460.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3324.05

LogP -28.50

H-bond Donors 127.0

H-bond Acceptors 117.0

Rotatable Bonds 275.0

Heavy Atoms 570.0

Ring Count 10.0

Amide Bonds 69.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0215872 VERIFIED: NO

Provenance & Taxonomy

OrganismPan troglodytes [Animal]

FamilyDefensin

Tax ID9598

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

RECORD: Rec_0401140 VERIFIED: NO