Peptide Database

Peptide NameF3Cys tumor-homing peptide

Function Ontology

Anticancer

Anticancer ▸ Tumor Homing Peptide

Delivery / Targeting ▸ Drug delivery vehicle

Standard StatusStandard

Sequence Length32 amino acids

Chemical FormulaC155H268N50O42S

DescriptionStandard

        KDEPQRRSARLSAKPAPPKPEPKPKKAPAKKC
    

Molecular Weight3536.16 Da

Isoelectric Point (pI)10.46

Net Charge (pH 7.0)7.75

Net Charge (pH 7.4) 7.52

Charge Density (pH 7.0) 0.2422

GRAVY Index-1.81

Hydrophobic Moment 0.66

Boman Index-0.56

Instability Index87.83

Aliphatic Index 27.81

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1484.41

LogP -16.17

H-bond Donors 49.0

H-bond Acceptors 51.0

Rotatable Bonds 115.0

Heavy Atoms 248.0

Ring Count 8.0

Amide Bonds 32.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0042601 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Tumor-homing Cell-penetrating Drug delivery Protein-binding

TargetMDA-MB-435 cells; MDA-MB-435 xenografts; A549 xenografts; cell-surface nucleolin

MethodFluorescence localization; cellular uptake; in vivo tumor imaging

RECORD: Rec_0067085 VERIFIED: YES