Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length264 amino acids

Chemical FormulaC1344H2111N337O393S7

DescriptionStandard

        MEKPILKNLNEMLCPIVTSEVEALNANLSMLEVITKIDNYTLLDYSLISSPYTTENYTELHLKGVFYPLGNLTDPPFALVPFVLPERSDSMLYIGISEYFFKSASHAYFTAGAFNITLSTKEITDHLMQTSQGLGNVLSRVASTNVALVILGQRLICSLSLNRFHLSLPESSRSNIEVLRFENILSSILHFGVLPLANAKLQQGFPLPNPHKISLVNSDIEVLEGFLLISTDLKYETSLKQQPSFHGWESLNLISGQWREKPAP
    

Molecular Weight29502.61 Da

Isoelectric Point (pI)5.49

Net Charge (pH 7.0)-6.87

Net Charge (pH 7.4) -7.53

Charge Density (pH 7.0) -0.0260

GRAVY Index0.09

Hydrophobic Moment 0.63

Boman Index0.15

Instability Index46.68

Aliphatic Index 108.56

Aromaticity 0.0909

Extinction Coeff. Reduced 24410.00

Extinction Coeff. Oxidized 24535.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0338938 VERIFIED: NO

Provenance & Taxonomy

OrganismCatagonus wagneri [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria

MethodQualitative functional evidence