Peptide Database

Peptide NameBrevinin-1HSa

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length24 amino acids

Chemical FormulaC121H204N30O27S2

DescriptionStandard

        FLPAVLRVAAKIVPTVFCAISKKC
    

Molecular Weight2575.23 Da

Isoelectric Point (pI)9.85

Net Charge (pH 7.0)3.74

Net Charge (pH 7.4) 3.50

Charge Density (pH 7.0) 0.1557

GRAVY Index1.26

Hydrophobic Moment 0.65

Boman Index0.32

Instability Index34.61

Aliphatic Index 130.00

Aromaticity 0.0833

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 895.46

LogP -4.18

H-bond Donors 33.0

H-bond Acceptors 33.0

Rotatable Bonds 81.0

Heavy Atoms 180.0

Ring Count 4.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0375173 VERIFIED: YES

Provenance & Taxonomy

OrganismRana hosii [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus ATCC 25923

Activity3 μM

MethodMIC

RECORD: Rec_0417439 VERIFIED: YES

Provenance & Taxonomy

OrganismRana hosii [Animal]

FamilyBrevinin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermCyclization

Disulfide18-24