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MYP_080058
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Basic Information
Unnamed
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxin
Venom / Toxin ▸ Toxin
Standard
46 amino acids
C201H334N62O64S6
Standard
Sequence
KSCCPNTTGRNIYNACRLTGAPRPTCAKLSGCKIISGSTCPSDYPK
Physicochemical Analysis
4835.57 Da
9.30
5.70
5.40
0.1238
-0.46
0.67
-0.11
49.56
48.91
0.0435
2980.00
3355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2027.98
-29.69
77.0
76.0
152.0
333.0
7.0
48.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0039635 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0049814 VERIFIED: NO
Provenance & Taxonomy
Viscum album [Plant]
Thionin
3972
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
disulfide-stabilized; exact pairings not extracted
Bio-Activity Profile
Anticancer Antimicrobial
PaperPlant Antimicrobial Oligopeptides with Anticancer Properties as a Source of Biologically Active Peptides—An In Silico Study PMID41009751 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/41009751/
RECORD: Rec_0083741 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperSchrader G., Apel K.;. Isolation and characterization of cDNAs encoding viscotoxins of mistletoe (Viscum album)."; Eur. J. Biochem. 198:549-553. Evidence URLhttps://www.uniprot.org/uniprotkb/THN3_VISAL/entry
RECORD: Rec_0104905 VERIFIED: YES
Provenance & Taxonomy
Viscum album [Plant]
Defensin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antifungal Cytotoxic
Sclerotinia sclerotiorum
PaperPubMed PMID: 1710983 | PubMed PMID: 4941626 | PubMed PMID: 10947973 PMID1710983;4941626;10947973 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1710983/
RECORD: Rec_0139895 VERIFIED: YES
Provenance & Taxonomy
Viscum album [Plant]
Thionin
3972
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
multiple disulfide bonds reported, sites not specified
Bio-Activity Profile
Antimicrobial Antifungal
Fusarium solani
PaperPubMed PMID 1094797 | PubMed PMID 3571916 | PubMed PMID 6000000 | Tabiasco et al., 2002 | Acta Cryst 2003; D59: 2125-32 PMID1094797;3571916;6000000;10947973;57191;66000 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1094797/
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