Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length151 amino acids

Chemical FormulaC755H1178N212O219S7

DescriptionStandard

        MSKVQFKPRAVTEAIFVHCSATKASMNVGLREIRQWHKEQGWLDVGYHFIIRRDGTIEEGRPVDVVGSHVKDWNSKSVGVCLVGGIDDKGKFEANFTPAQMQSLKEKLADLKDMYPDAEIKAHHDVAPKACPSFNLSRWLKTGELVTSDWG
    

Molecular Weight16953.17 Da

Isoelectric Point (pI)7.76

Net Charge (pH 7.0)1.02

Net Charge (pH 7.4) 0.41

Charge Density (pH 7.0) 0.0067

GRAVY Index-0.43

Hydrophobic Moment 0.75

Boman Index-0.03

Instability Index39.69

Aliphatic Index 75.50

Aromaticity 0.0861

Extinction Coeff. Reduced 30480.00

Extinction Coeff. Oxidized 30605.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6922.14

LogP -64.87

H-bond Donors 242.0

H-bond Acceptors 233.0

Rotatable Bonds 566.0

Heavy Atoms 1193.0

Ring Count 30.0

Amide Bonds 159.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0195951 VERIFIED: NO

Provenance & Taxonomy

OrganismShigella phage VB_Ship_A7 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic