Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC355H581N101O86S8

DescriptionStandard

        MKLLLLTLAVLLLLSQLMPGGTQKCWNLHGRCRQKCSKRERAYVYCTNNKLCCVKPKFQPREKLWPF
    

Molecular Weight7896.56 Da

Isoelectric Point (pI)9.93

Net Charge (pH 7.0)10.52

Net Charge (pH 7.4) 10.15

Charge Density (pH 7.0) 0.1571

GRAVY Index-0.21

Hydrophobic Moment 0.43

Boman Index-0.08

Instability Index37.01

Aliphatic Index 91.64

Aromaticity 0.0896

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3044.52

LogP -22.30

H-bond Donors 112.0

H-bond Acceptors 106.0

Rotatable Bonds 265.0

Heavy Atoms 550.0

Ring Count 13.0

Amide Bonds 73.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0100252 VERIFIED: NO

Provenance & Taxonomy

OrganismMustela putorius furo [Animal]

FamilyDefensin

Tax ID9669

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence