Peptide Database

Peptide NameCathepsin G (EC 3.4.21.20) (Vimentin-specific protease) (VSP)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium

Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Protease

Enzyme / Catalytic activity ▸ Protease ▸ Serine protease

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length261 amino acids

Chemical FormulaC1274H2058N390O363S14

DescriptionStandard

        MQPLLLLLTFILLQGDEAGKIIGGREARPHSYPYMAFLLIQSPEGLSACGGFLVREDFVLTAAHCLGSSINVTLGAHNIQMRERTQQLITVLRAIRHPDYNPQNIRNDIMLLQLRRRARRSGSVKPVALPQASKKLQPGDLCTVAGWGRVSQSRGTNVLQEVQLRVQMDQMCANRFQFYNSQTQICVGNPRERKSAFRGDSGGPLVCSNVAQGIVSYGSNNGNPPAVFTKIQSFMPWIKRTMRRFAPRYQRPANSLSQAQT
    

Molecular Weight29095.27 Da

Isoelectric Point (pI)10.57

Net Charge (pH 7.0)17.80

Net Charge (pH 7.4) 17.26

Charge Density (pH 7.0) 0.0682

GRAVY Index-0.29

Hydrophobic Moment 0.81

Boman Index-0.04

Instability Index57.78

Aliphatic Index 84.83

Aromaticity 0.0690

Extinction Coeff. Reduced 19940.00

Extinction Coeff. Oxidized 20315.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0063104 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyPeptidase S1

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antibiofilm Anti-tuberculosis Anti-Gram-negative Anti-Gram-positive Hydrolase Protease Serine protease Cytotoxic Proteolytic Non-hemolytic

TargetStaphylococcus aureus (Gram-positive)

RECORD: Rec_0213582 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyPeptidase S1

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antibiofilm Anti-tuberculosis Anti-Gram-negative Anti-Gram-positive Hydrolase Protease Serine protease Cytotoxic Proteolytic Non-hemolytic

TargetN. gonorrhoeae (Gram-negative)

RECORD: Rec_0218814 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyPeptidase S1

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antibiofilm Anti-tuberculosis Anti-Gram-negative Anti-Gram-positive Hydrolase Protease Serine protease Cytotoxic Proteolytic Non-hemolytic

TargetM. tuberculosis (Gram-positive)