Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length77 amino acids

Chemical FormulaC392H637N113O110S9

DescriptionStandard

        MKTGLFLFAALFFLAPGKNEFFDEKCYQLKGKCMRHCQKNEELVALCQKSLKCCLTKQRGREKEEGGREGKRKEMDK
    

Molecular Weight8981.53 Da

Isoelectric Point (pI)9.26

Net Charge (pH 7.0)6.54

Net Charge (pH 7.4) 6.15

Charge Density (pH 7.0) 0.0850

GRAVY Index-0.79

Hydrophobic Moment 0.54

Boman Index-0.24

Instability Index27.72

Aliphatic Index 54.55

Aromaticity 0.0909

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3692.33

LogP -33.18

H-bond Donors 133.0

H-bond Acceptors 127.0

Rotatable Bonds 324.0

Heavy Atoms 624.0

Ring Count 9.0

Amide Bonds 82.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0278114 VERIFIED: NO

Provenance & Taxonomy

OrganismSpermophilus dauricus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence