Peptide Database

Peptide NameL-amino-acid oxidase (LAAO) (LAO) (EC 1.4.3.2)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Enzyme / Catalytic activity ▸ Oxidoreductase

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length95 amino acids

Chemical FormulaC500H764N132O158S2

DescriptionStandard

        DDRRSPLEECFQQNDYEEFLEIARNSQLYQESLREDSSYHLSFIESLKSDALFSYEKKFWEADGIHGGKVINDLSLIHDLPKREIQALCYPSIKK
    

Molecular Weight11216.33 Da

Isoelectric Point (pI)4.86

Net Charge (pH 7.0)-6.97

Net Charge (pH 7.4) -7.40

Charge Density (pH 7.0) -0.0734

GRAVY Index-0.76

Hydrophobic Moment 0.54

Boman Index-0.14

Instability Index70.03

Aliphatic Index 81.16

Aromaticity 0.1158

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13075.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4742.92

LogP -43.22

H-bond Donors 164.0

H-bond Acceptors 156.0

Rotatable Bonds 382.0

Heavy Atoms 792.0

Ring Count 18.0

Amide Bonds 102.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0096483 VERIFIED: YES

Provenance & Taxonomy

OrganismNaja oxiana [Animal]

FamilyFlavin monoamine oxidase; FIG1 subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antiparasitic Anti-Gram-negative Anti-Gram-positive Oxidoreductase Antiplatelet Cytolytic Toxin Hemolytic

TargetEscherichia coli (Gram-negative)

RECORD: Rec_0120375 VERIFIED: YES

Provenance & Taxonomy

OrganismNaja oxiana [Animal]

FamilyFlavin monoamine oxidase; FIG1 subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antiparasitic Anti-Gram-negative Anti-Gram-positive Oxidoreductase Antiplatelet Cytolytic Toxin Hemolytic

TargetBacillus subtilis (Gram-positive)

RECORD: Rec_0214540 VERIFIED: YES

Provenance & Taxonomy

OrganismNaja oxiana [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antiparasitic

TargetEscherichia coli

RECORD: Rec_0264717 VERIFIED: YES

Provenance & Taxonomy

OrganismNaja oxiana [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antiparasitic

TargetBacillus subtilis

RECORD: Rec_0271015 VERIFIED: YES

Provenance & Taxonomy

OrganismNaja oxiana [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antiparasitic