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MYP_079884
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Basic Information
Conorfamide-Sr1
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
12 amino acids
C73H98N16O14S
Standard
Sequence
GPMGWVPVFYRF
Physicochemical Analysis
1455.72 Da
8.75
0.76
0.55
0.0633
0.43
0.40
0.41
51.27
48.33
0.3333
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
463.76
0.49
16.0
16.0
38.0
104.0
7.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0081288 VERIFIED: NO
Provenance & Taxonomy
Conus spurius [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Neuropeptide
RECORD: Rec_0118848 VERIFIED: YES
Provenance & Taxonomy
Conus spurius [Animal]
FMRFamide related peptide
192919
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
RFamide Neuropeptide Neuromodulator
PMID11738233 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11738233/
RECORD: Rec_0152315 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 50.0%, C 50.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Toxic Cytotoxic
PaperIn silico approach for predicting toxicity of peptides and proteins PMID24058508 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24058508/
RECORD: Rec_0262954 VERIFIED: YES
Provenance & Taxonomy
Conus spurius [Animal]
Conorfamide-Sr1
192919
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
-
Mammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Conorfamide-Sr1 (Conus spurius): PMID 11738233 PMID11738233 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11738233/
RECORD: Rec_0279041 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 25.0%, E 0.0%, T 33.3%, C 41.7% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Miscellaneous
PaperConoServer: updated content, knowledge, and discovery tools in the conopeptide database PMID22058133 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22058133/
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