Peptide Database

Peptide NamekCA2 (Kallikrein inhibitor with internal arginines)

Function Ontology

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC72H114N24O26S3

DescriptionStandard

        ACSDRFRNCPADEALCG
    

Molecular Weight1828.02 Da

Isoelectric Point (pI)4.56

Net Charge (pH 7.0)-1.23

Net Charge (pH 7.4) -1.46

Charge Density (pH 7.0) -0.0723

GRAVY Index-0.37

Hydrophobic Moment 0.37

Boman Index-0.18

Instability Index54.05

Aliphatic Index 40.59

Aromaticity 0.0588

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 819.15

LogP -11.36

H-bond Donors 31.0

H-bond Acceptors 28.0

Rotatable Bonds 57.0

Heavy Atoms 125.0

Ring Count 2.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0266789 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilykCA2

Tax ID32630

Structure & Mods

Configcyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermExtended with Alanine and an 6-aminohexanoic acid (Ahx) spacer

C-TermAmidation

Bio-Activity Profile

Function

Cell-penetrating peptide Cargo delivery