Peptide Database

Peptide NameCathelicidin-B1 (CATH-B1)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length251 amino acids

Chemical FormulaC1189H1900N348O350S8

DescriptionStandard

        MGRMWASEVLLLLLLGSSRAVTPGLDVSTAPGLDGSIPPGLDGSVSPGLDGSVSPGLDGSASPGLDGSVSPGLDGSASPGLDGSTPAGRDGTITPKLEGTITPKQDGSISPSWPWRWPITYLDAILAAVRLLNQKISGPCILRLREAQPRPGWVGTLQRRREVSFLVEDGPCPPGVDCRSCEPGALQHCVGTVSIEQQPTAELRCRPLRPQPIRNWWIRIWEWLNGIRKRLRQRSPFYVRGHLNVTSTPQP
    

Molecular Weight26926.45 Da

Isoelectric Point (pI)8.88

Net Charge (pH 7.0)3.65

Net Charge (pH 7.4) 3.21

Charge Density (pH 7.0) 0.0145

GRAVY Index-0.27

Hydrophobic Moment 0.65

Boman Index0.02

Instability Index58.50

Aliphatic Index 87.37

Aromaticity 0.0518

Extinction Coeff. Reduced 52480.00

Extinction Coeff. Oxidized 52855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0424252 VERIFIED: YES

Provenance & Taxonomy

OrganismGallus gallus [Animal]

FamilyCathelicidin

Tax ID9031

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetGram Negative Bacteria and Gram Positive Bacteria