Peptide Database

Peptide NameGlucagon-like peptide 2

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC148H221N41O50

DescriptionStandard

        HADGTYTSDVSSYLQDQAAKDFVSWLKAGRG
    

Molecular Weight3374.58 Da

Isoelectric Point (pI)5.36

Net Charge (pH 7.0)-1.15

Net Charge (pH 7.4) -1.41

Charge Density (pH 7.0) -0.0372

GRAVY Index-0.64

Hydrophobic Moment 0.60

Boman Index-0.04

Instability Index20.47

Aliphatic Index 56.77

Aromaticity 0.1290

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1491.95

LogP -18.17

H-bond Donors 53.0

H-bond Acceptors 50.0

Rotatable Bonds 109.0

Heavy Atoms 239.0

Ring Count 6.0

Amide Bonds 32.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0150656 VERIFIED: NO

Provenance & Taxonomy

OrganismLophius americanus [Animal]

FamilyGlucagon

Tax ID8073

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Metabolic

RECORD: Rec_0180706 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0301720 VERIFIED: NO

Provenance & Taxonomy

OrganismLophius americanus [Animal]

FamilyGlucagon-like peptide

Tax ID8073

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 3.5 hour; Yeast: 10 min; E. coli: >10 hour