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MYP_079802
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Basic Information
Leucrocin I
Anticancer
Anticancer ▸ Antitumor
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
7 amino acids
C36H56N10O11
Standard
Sequence
NGVQPKY
Physicochemical Analysis
804.89 Da
8.59
0.76
0.55
0.1083
-1.43
0.17
-0.17
14.61
41.43
0.1429
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
361.56
-3.68
11.0
12.0
24.0
57.0
2.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0138811 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
200
MIC
PMID23831136 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23831136/
RECORD: Rec_0181443 VERIFIED: YES
Provenance & Taxonomy
Crocodylus siamensis [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus epidermidis
25 μg/mL
MIC
PaperCharacterization of the novel antibacterial peptide Leucrocin from crocodile (Crocodylus siamensis) white blood cell extracts.
RECORD: Rec_0209376 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Toxic Hemolytic Anti-Gram-positive Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0235702 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 25923
200
MIC
PMID23831136 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23831136/
RECORD: Rec_0272819 VERIFIED: YES
Provenance & Taxonomy
Crocodylus siamensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anticancer Antitumor Mammalian Cell
Staphylococcus epidermidis ATCC 12228
200 μg/mL
MIC
PMID21184776;23831136;27129462;24192554 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21184776/
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