Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length79 amino acids

Chemical FormulaC372H606N92O97S4

DescriptionStandard

        MVSMLPVADMVKEFGVPAVAAGAVVKILEGVDWLITGAAILAAIGTGGASLVAAAGKESLKAFLKRKFGEMGKKAFIAW
    

Molecular Weight8047.61 Da

Isoelectric Point (pI)9.52

Net Charge (pH 7.0)2.51

Net Charge (pH 7.4) 2.27

Charge Density (pH 7.0) 0.0317

GRAVY Index0.82

Hydrophobic Moment 0.74

Boman Index0.35

Instability Index17.71

Aliphatic Index 112.53

Aromaticity 0.0759

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2942.13

LogP -18.81

H-bond Donors 102.0

H-bond Acceptors 104.0

Rotatable Bonds 269.0

Heavy Atoms 565.0

Ring Count 10.0

Amide Bonds 78.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0085187 VERIFIED: NO

Provenance & Taxonomy

OrganismPaenibacillus thiaminolyticus [Bacterium]

FamilyCircular bacteriocin

Structure & Mods

Configcyclic peptide topology reported [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Non-hemolytic Non-ribosomal