Peptide Database

Peptide NameaStAx-35

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC100H159N37O23

DescriptionStandard

        RRWPQSILDSHVRRVWR
    

Molecular Weight2247.57 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)3.85

Net Charge (pH 7.4) 3.59

Charge Density (pH 7.0) 0.2264

GRAVY Index-1.24

Hydrophobic Moment 0.79

Boman Index-0.52

Instability Index170.33

Aliphatic Index 80.00

Aromaticity 0.1176

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1010.74

LogP -8.48

H-bond Donors 39.0

H-bond Acceptors 28.0

Rotatable Bonds 71.0

Heavy Atoms 160.0

Ring Count 6.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0192135 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyAxin-derived

Tax ID32630

Structure & Mods

Confighydrocarbon-stapled side-chain cyclic peptide [Cyclic]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermAcetylation

C-TermAmidation

Other ModsStapled: Ⓧ(6) and Ⓧ (10) are cross-linked by hydrocarbon stapling

Bio-Activity Profile

Function

Anticancer Antimicrobial Antibacterial