Peptide Database

Peptide NameAngiotensin I-converting enzyme-inhibitory peptide IW-11

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length11 amino acids

Chemical FormulaC53H82N16O15S

DescriptionStandard

        IVRDPNGMGAW
    

Molecular Weight1215.38 Da

Isoelectric Point (pI)5.84

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.44

Charge Density (pH 7.0) -0.0217

GRAVY Index-0.22

Hydrophobic Moment 0.36

Boman Index0.13

Instability Index-20.01

Aliphatic Index 70.91

Aromaticity 0.0909

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 503.61

LogP -4.17

H-bond Donors 17.0

H-bond Acceptors 16.0

Rotatable Bonds 36.0

Heavy Atoms 85.0

Ring Count 3.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0106415 VERIFIED: YES

Provenance & Taxonomy

OrganismPelodiscus sinensis [Animal]

FamilyAngiotensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory ACE inhibitory

TargetAngiotensin-I converting enzyme

Activity4.39±0.31 μM

MethodIC50

RECORD: Rec_0266598 VERIFIED: YES

Provenance & Taxonomy

OrganismGallus gallus [Animal]

Tax ID9031.0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antihypertensive ACE inhibitory

TargetAngiotensin-converting enzyme (ACE)