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MYP_079750
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Basic Information
Cecropin A (1-7) + Melittine (2-9) [L4K][A10K]
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
15 amino acids
C92H159N23O16
Standard
Sequence
KWKKFKKIGKVLKVL
Physicochemical Analysis
1843.39 Da
10.78
6.75
6.54
0.4502
-0.35
0.76
-0.16
-28.99
116.67
0.1333
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
668.65
0.14
24.0
23.0
69.0
131.0
3.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0010116 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus epidermidis
0.25 μM
MIC
PMID18852279 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18852279/
RECORD: Rec_0018872 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli BL21
0.5 μM
MIC
PMID18852279 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18852279/
RECORD: Rec_0042151 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
9 % hemolysis at 64 μM
Hemolysis
PMID18852279 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18852279/
RECORD: Rec_0208174 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 6538P
16 μM
MIC
PMID18852279 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18852279/
RECORD: Rec_0354441 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 26.7%, E 0.0%, T 53.3%, C 20.0% [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Toxic Antimicrobial Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
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