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MYP_079718
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Basic Information
[F30A]cHLH-p53-R
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
39 amino acids
C185H324N62O48S
Standard
Sequence
GARELRRLERELRRLEGGGGGGGKLAALKAKLLWLKLAC
Physicochemical Analysis
4217.00 Da
10.91
5.76
5.53
0.1476
-0.29
1.12
-0.14
73.24
112.82
0.0256
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1809.59
-15.36
68.0
55.0
152.0
296.0
2.0
38.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0051083 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
CAA, Chloroacetic acid
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human erythrocytes
>64 μM
Hemolysis
PMID31390185 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31390185/
RECORD: Rec_0100540 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
CAA, Chloroacetic acid
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
HFF-1
64 μM
CC50
PMID31390185 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31390185/
RECORD: Rec_0128366 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
CAA, Chloroacetic acid
None
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: K562
36.7±1.9 μM
CC50
PMID31390185 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31390185/
RECORD: Rec_0239079 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
CAA, Chloroacetic acid
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
MCF-10A
64 μM
CC50
PMID31390185 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31390185/
RECORD: Rec_0298694 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
CAA, Chloroacetic acid
None
Bio-Activity Profile
Antimicrobial Anticancer
MDA-MB-435S
32 μM
CC50
PMID31390185 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31390185/
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