Peptide Database

Peptide NameXTH_TOBAC

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Neurological / Signaling ▸ Signaling peptide

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length295 amino acids

Chemical FormulaC1547H2316N406O437S9

DescriptionStandard

        AFQDLDALQYRRLRWVRQKYTIYNYCTDRKRYPTLPPECTKDRDIATRGGLEKTDWSNAPFTASYTSFHVDGCEAATPQEVQVCNTKGMRWWDQKGSTVDLVLDRSSGAGFQSKKSYLFGHFSMKLKLVGGDSAGVVTAFYLSSNMGVKGLLFSIVLINLSLLGLCGYPRKPVDVPFWKNYEPSWASHHIKYLSGNAEHDEIDFEFLGNRTGQPYILQTNVFTGGKGDREQRIYLWFDPTKGYHSYSVLWNTFQIVIFVDDVPIRAFKNSKDLGVKFPFNQPMKIYSSLWDADDW
    

Molecular Weight33881.98 Da

Isoelectric Point (pI)8.65

Net Charge (pH 7.0)4.28

Net Charge (pH 7.4) 3.63

Charge Density (pH 7.0) 0.0145

GRAVY Index-0.42

Hydrophobic Moment 0.55

Boman Index0.01

Instability Index35.25

Aliphatic Index 72.34

Aromaticity 0.1492

Extinction Coeff. Reduced 78840.00

Extinction Coeff. Oxidized 79090.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0221246 VERIFIED: YES

Provenance & Taxonomy

OrganismNicotiana tabacum [Plant]

Tax ID4097

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond reported, sites not specified

Other ModsGlycosylation reported

Bio-Activity Profile

Function

Signaling Enzyme inhibitory ACE inhibitory Antihypertensive

TargetAngiotensin-converting enzyme