Peptide Database

Peptide NamePhylloseptin-S2

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Antiparasitic ▸ Antiprotozoal

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC98H154N24O23

DescriptionStandard

        FLSLIPHIVSGVASLAKHF
    

Molecular Weight2036.42 Da

Isoelectric Point (pI)8.76

Net Charge (pH 7.0)0.93

Net Charge (pH 7.4) 0.63

Charge Density (pH 7.0) 0.0491

GRAVY Index1.23

Hydrophobic Moment 0.49

Boman Index0.50

Instability Index21.16

Aliphatic Index 143.68

Aromaticity 0.1053

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 722.40

LogP -3.63

H-bond Donors 25.0

H-bond Acceptors 26.0

Rotatable Bonds 63.0

Heavy Atoms 145.0

Ring Count 5.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0387742 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyllomedusa sauvagii [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Anticancer Hemolytic

TargetHuman erythrocytes

Activity25 μM

MethodLC50

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