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MYP_079635
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Basic Information
Phylloseptin-S2
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
19 amino acids
C98H154N24O23
Standard
Sequence
FLSLIPHIVSGVASLAKHF
Physicochemical Analysis
2036.42 Da
8.76
0.93
0.63
0.0491
1.23
0.49
0.50
21.16
143.68
0.1053
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
722.40
-3.63
25.0
26.0
63.0
145.0
5.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0251543 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human erythrocytes
25 μM
Hemolysis
PMID23967105 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23967105/
RECORD: Rec_0261564 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Pseudomonas aeruginosa ATCC 27853
200 μM
MIC
PMID23967105 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23967105/
RECORD: Rec_0272657 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Enterococcus faecalis ATCC 29212
25 μM
MIC
PMID23967105 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23967105/
RECORD: Rec_0283232 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Saccharomyces cerevisiae
6.25 μM
MIC
PMID23967105 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23967105/
RECORD: Rec_0292182 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Leishmania braziliensis MHOM/BR/75/M2904
15 μM
IC50
PMID23967105 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23967105/
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