Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length90 amino acids

Chemical FormulaC474H737N121O137S9

DescriptionStandard

        MTVVEVWENVLNYLMKSFETGDKTLVFRPWKISNVSYSSFTVATCSLVDPDRCTKIFGYCRRRCFKYEKQIDVCLSPSKICCIERLFEED
    

Molecular Weight10611.24 Da

Isoelectric Point (pI)7.50

Net Charge (pH 7.0)0.45

Net Charge (pH 7.4) 0.10

Charge Density (pH 7.0) 0.0050

GRAVY Index-0.12

Hydrophobic Moment 0.61

Boman Index-0.03

Instability Index40.80

Aliphatic Index 77.78

Aromaticity 0.1333

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 17335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4196.07

LogP -35.51

H-bond Donors 156.0

H-bond Acceptors 147.0

Rotatable Bonds 350.0

Heavy Atoms 741.0

Ring Count 17.0

Amide Bonds 93.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0073547 VERIFIED: NO

Provenance & Taxonomy

OrganismUrsus maritimus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence