Peptide Database

Peptide NameCycloviolacin H4

Function Ontology

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Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC130H211N35O39S6

DescriptionStandard

        GIPCGESCVWIPCLTSTVGCSCKSKVCYR
    

Molecular Weight3080.67 Da

Isoelectric Point (pI)8.33

Net Charge (pH 7.0)1.70

Net Charge (pH 7.4) 1.40

Charge Density (pH 7.0) 0.0586

GRAVY Index0.46

Hydrophobic Moment 0.29

Boman Index0.15

Instability Index18.42

Aliphatic Index 70.34

Aromaticity 0.0690

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1169.18

LogP -13.65

H-bond Donors 48.0

H-bond Acceptors 47.0

Rotatable Bonds 95.0

Heavy Atoms 210.0

Ring Count 5.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0302078 VERIFIED: YES

Provenance & Taxonomy

OrganismViola biflora [Plant]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)