Peptide Database

Peptide NameGuanilate cyclase C activating peptide II

Function Ontology

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length24 amino acids

Chemical FormulaC108H180N30O36S4

DescriptionStandard

        FKTLRTIANDDCELCVNVACTGCL
    

Molecular Weight2603.02 Da

Isoelectric Point (pI)4.56

Net Charge (pH 7.0)-1.28

Net Charge (pH 7.4) -1.54

Charge Density (pH 7.0) -0.0531

GRAVY Index0.51

Hydrophobic Moment 0.49

Boman Index0.10

Instability Index44.58

Aliphatic Index 97.50

Aromaticity 0.0417

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1079.31

LogP -12.22

H-bond Donors 41.0

H-bond Acceptors 39.0

Rotatable Bonds 85.0

Heavy Atoms 178.0

Ring Count 1.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0298147 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Tax ID9606

Structure & Mods

Configdisulfide-stabilized linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide12-20; 15-23

Bio-Activity Profile

Function

CGMP Activator

RECORD: Rec_0304986 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGuanylate cyclase C-activating peptide

Tax ID9606

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide12-20; 15-23

Bio-Activity Profile

Function

Receptor modulation

Half-LifeMammalian: 1.1 hour; Yeast: 3 min; E. coli: 2 min