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MYP_079538
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Basic Information
Chromacin (mammals, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Cardiovascular
Hormonal / Endocrine ▸ Hormone peptide
Hormonal / Endocrine ▸ Secretory pathway peptide ▸ Secretory granule peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Cell-cell communication
Standard
22 amino acids
C97H151N29O37
Standard
Sequence
YPGPQAKEDSEGPSQGPASREK
Physicochemical Analysis
2315.41 Da
4.87
-1.23
-1.45
-0.0561
-1.86
0.29
-0.34
85.19
9.09
0.0455
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1069.50
-15.42
34.0
36.0
73.0
163.0
5.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0064196 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Micrococcus luteus
PaperPubMed PMID: 8910482 PMID8910482 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8910482/
RECORD: Rec_0068678 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0073190 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperStrub J.-M., Goumon Y., Lugardon K., Capon C., Lopez M., Moniatte M., van Dorsselaer A., Aunis D., Metz-Boutigue M.-H.;. "Antibacterial activity of glycosylated and phosphorylated chromogranin A-derived peptide 173-194 from bovine adrenal medullary chromaffin granules."; J. Biol. Chem. 271:28533-28540. Evidence URLhttps://www.uniprot.org/uniprotkb/CMGA_BOVIN/entry
RECORD: Rec_0092505 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Chromogranin/secretogranin
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Phosphotyrosine
Ser10 Phosphoserine
Bio-Activity Profile
Secretory granule peptide Neuropeptide precursor
PMID8910482 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8910482/
RECORD: Rec_0166785 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Chromacin
9913
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
1:Phosphotyrosine; 10:Phosphoserine; 14:O-linked (GalNAc...) serine
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Antibacterial Hormone Endocrine Cardiovascular Receptor modulation Immunomodulatory
Mammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for Chromacin (Bos taurus): PMID 8910482 PMID8910482 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8910482/
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