MYP_079484
E2EM15W-S3
Antimicrobial
Antimicrobial
▸
Antibacterial
Standard
15 amino acids
C77H131N21O20
Standard
TLKQWAKGVGKDLVK
1670.99 Da
10.00
2.40
2.20
0.1597
-0.48
0.64
-0.08
-9.49
97.33
0.0667
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
691.21
-4.77
24.0
23.0
59.0
118.0
2.0
15.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0005016
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
hydrocarbon-stapled side-chain cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
The Ⓧ (position: 6 and 10) in sequence indicates (S)-α-methyl, α-pentenylglycine. Ⓧ (6) and Ⓧ (10) are cross-linked by hydrocarbon stapling through an oct-4-enyl staple
Bio-Activity Profile
Antimicrobial
Antibacterial
Staphylococcus aureus
6.25 μg/mL
MIC
RECORD: Rec_0032339
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
hydrocarbon-stapled side-chain cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
The Ⓧ (position: 6 and 10) in sequence indicates (S)-α-methyl, α-pentenylglycine. Ⓧ (6) and Ⓧ (10) are cross-linked by hydrocarbon stapling through an oct-4-enyl staple
Bio-Activity Profile
Antimicrobial
Antibacterial
Pseudomonas aeruginosa
>200 μg/mL
MIC
RECORD: Rec_0084802
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
hydrocarbon-stapled side-chain cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
The Ⓧ (position: 6 and 10) in sequence indicates (S)-α-methyl, α-pentenylglycine. Ⓧ (6) and Ⓧ (10) are cross-linked by hydrocarbon stapling through an oct-4-enyl staple
Bio-Activity Profile
Antimicrobial
Antibacterial
Proteus mirabilis
>200 μg/mL
MIC
RECORD: Rec_0099024
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
hydrocarbon-stapled side-chain cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
The Ⓧ (position: 6 and 10) in sequence indicates (S)-α-methyl, α-pentenylglycine. Ⓧ (6) and Ⓧ (10) are cross-linked by hydrocarbon stapling through an oct-4-enyl staple
Bio-Activity Profile
Antimicrobial
Antibacterial
Staphylococcus epidermidis
100 μg/mL
MIC
RECORD: Rec_0100116
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
hydrocarbon-stapled side-chain cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
The Ⓧ (position: 6 and 10) in sequence indicates (S)-α-methyl, α-pentenylglycine. Ⓧ (6) and Ⓧ (10) are cross-linked by hydrocarbon stapling through an oct-4-enyl staple
Bio-Activity Profile
Antimicrobial
Antibacterial
Bacillus subtilis
6.25 μg/mL
MIC
Showing 5 records on this page · Page 1 of 2