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MYP_079475
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Basic Information
(IR)2-Protegrin 1 (8-13)-(RI)2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
14 amino acids
C81H149N35O15S2
Standard
Sequence
IRIRCRRRFCRIRI
Physicochemical Analysis
1917.41 Da
12.00
6.74
6.51
0.4814
-0.41
0.48
-0.74
91.11
111.43
0.0714
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
874.92
-7.17
38.0
24.0
67.0
133.0
1.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0152449 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Klebsiella pneumoniae ATCC 700603
8 μM
MIC
PMID24952979 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24952979/
RECORD: Rec_0153597 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis
4 μM
MIC
PMID24621994 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24621994/
RECORD: Rec_0155166 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
5-10
Bio-Activity Profile
Antimicrobial
S. faecalis ATCC 29212
4 μM
MIC
PaperAntimicrobial potency and selectivity of simplified symmetric-end peptides.
RECORD: Rec_0180607 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
human red blood cells
PMID24621994 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24621994/
RECORD: Rec_0183178 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Salmonella typhimurium
4 μM
MIC
PMID24621994 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24621994/
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