Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length115 amino acids

Chemical FormulaC575H943N157O157S11

DescriptionStandard

        MFWTPGSATFFLKTMKLLLLTLTVCLILFQILPVCRGQKSCWIIKGHCRKNCKSGEQVKKPCKNGDYCCILSKTDSQPHRLTQAPTGKSQILSTDLEGNDVLEHVPLVIMRQGKI
    

Molecular Weight12920.31 Da

Isoelectric Point (pI)9.36

Net Charge (pH 7.0)8.68

Net Charge (pH 7.4) 8.17

Charge Density (pH 7.0) 0.0755

GRAVY Index-0.03

Hydrophobic Moment 0.57

Boman Index0.04

Instability Index25.91

Aliphatic Index 94.87

Aromaticity 0.0609

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5041.35

LogP -45.30

H-bond Donors 181.0

H-bond Acceptors 180.0

Rotatable Bonds 436.0

Heavy Atoms 900.0

Ring Count 18.0

Amide Bonds 124.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0254638 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus familiaris (Dog) [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin