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MYP_079443
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Basic Information
Pardaxin 3
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
33 amino acids
C160H250N36O47
Standard
Sequence
GFFAFIPKIISSPLFKTLLSAVGSALSSSGEQE
Physicochemical Analysis
3429.91 Da
6.28
-0.23
-0.44
-0.0070
0.62
0.50
0.34
39.34
100.61
0.1212
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1308.51
-12.59
45.0
47.0
111.0
243.0
6.0
33.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0010259 VERIFIED: YES
Provenance & Taxonomy
Peacock sole [Animal]; Actinopterygii [Animal]
33208; 7898
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID17737623 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17737623/
RECORD: Rec_0063927 VERIFIED: YES
Provenance & Taxonomy
Pardachirus pavoninus [Animal]
Pardaxin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID17737623 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17737623/
RECORD: Rec_0069727 VERIFIED: YES
Provenance & Taxonomy
Sea moses sole [Animal]
Pardaxin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperMelittin-Like Peptides from the Shark-Repelling Defense Secretion of the Sole Pardachirus pavoninus
RECORD: Rec_0147368 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0174216 VERIFIED: YES
Provenance & Taxonomy
Pardachirus pavoninus [Plant]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Cytotoxic
PaperPubMed PMID: 17737623 PMID17737623 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17737623/
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