Peptide Database

Peptide NameMacrophage migration inhibitory factor

Function Ontology

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC547H852N150O164S6

DescriptionStandard

        PMFIVNTNVPRASVPEGFLSELTQQLAQATGKPAQYIAVHVVPDQLMTFSGTSDPCALCSLHSIGKIGGAQNRNYSKLLCGLLSDRLHISPDRVYINYYDMNAANVGWNGSTFA
    

Molecular Weight12345.91 Da

Isoelectric Point (pI)7.28

Net Charge (pH 7.0)0.19

Net Charge (pH 7.4) -0.08

Charge Density (pH 7.0) 0.0017

GRAVY Index-0.02

Hydrophobic Moment 0.57

Boman Index0.13

Instability Index21.32

Aliphatic Index 87.28

Aromaticity 0.0877

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13075.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5001.57

LogP -54.71

H-bond Donors 173.0

H-bond Acceptors 173.0

Rotatable Bonds 395.0

Heavy Atoms 867.0

Ring Count 21.0

Amide Bonds 127.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0168086 VERIFIED: YES

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyMIF family

Tax ID10116; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other Mods77-Lys: N6-acetyllysine; alternate; 77-Lys: N6-succinyllysine; alternate

Bio-Activity Profile

Function

Cytokine Growth factor MIF family