Peptide Database

Peptide NamePap12-7

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC77H131N21O13

DescriptionStandard

        RWKIFKKVVKKV
    

Molecular Weight1559.00 Da

Isoelectric Point (pI)11.39

Net Charge (pH 7.0)5.76

Net Charge (pH 7.4) 5.54

Charge Density (pH 7.0) 0.4796

GRAVY Index-0.42

Hydrophobic Moment 0.82

Boman Index-0.28

Instability Index20.75

Aliphatic Index 105.00

Aromaticity 0.1667

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 591.21

LogP -0.38

H-bond Donors 22.0

H-bond Acceptors 19.0

Rotatable Bonds 56.0

Heavy Atoms 111.0

Ring Count 3.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0400758 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCecropin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-negative

TargetPseudomonas aeruginosa KCTC 2004

Activity4 μM

MethodMIC

FIRST PREV 1 2 3 4

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