Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length188 amino acids

Chemical FormulaC943H1488N258O252S9

DescriptionStandard

        PKALPMAREPMLLLAVTDFVANSAAFTYFTAGALHRNISSNMIPQKFPLQLRTKNMGVFSPQLQERYGDQPMELHLWARQQPLVSCHPDALHGTLFSSAEAFVVLPNTTRVPVFLLNIDANVTGTPTITRNRLGGTVRLTGVWGVLWIPCKAGLSLLQVKRLETLLKFGLWLFGVPRANSECCPHSAP
    

Molecular Weight20760.06 Da

Isoelectric Point (pI)9.70

Net Charge (pH 7.0)7.37

Net Charge (pH 7.4) 6.97

Charge Density (pH 7.0) 0.0392

GRAVY Index0.12

Hydrophobic Moment 0.54

Boman Index0.13

Instability Index46.16

Aliphatic Index 96.49

Aromaticity 0.0851

Extinction Coeff. Reduced 24980.00

Extinction Coeff. Oxidized 25230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8034.27

LogP -92.35

H-bond Donors 279.0

H-bond Acceptors 273.0

Rotatable Bonds 659.0

Heavy Atoms 1462.0

Ring Count 41.0

Amide Bonds 204.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0203514 VERIFIED: NO

Provenance & Taxonomy

OrganismCampylorhamphus procurvoides [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria