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MYP_079286
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Basic Information
Unnamed
Antimicrobial
Enzyme modulation ▸ Enzyme inhibition ▸ Inhibition of ileum cells contraction
Enzyme modulation ▸ Enzyme inhibition ▸ Inhibition of vas deferens cells contraction
Neurological / Signaling ▸ Analgesic/antinociceptive activity
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Standard
7 amino acids
C38H53N7O11
Standard
Sequence
YAFEVVG
Physicochemical Analysis
783.87 Da
4.05
-1.24
-1.44
-0.1769
1.11
0.34
0.57
30.27
97.14
0.2857
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
295.45
-0.67
10.0
10.0
22.0
56.0
2.0
6.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0009117 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0020761 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Opioid
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Opioid Analgesic Neuromodulator
PMID8394911 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8394911/
RECORD: Rec_0154107 VERIFIED: YES
Provenance & Taxonomy
Unknown [Animal]
Deltorphin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Myotropic
Mammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for Deltorphin II: PMID 8394911 PMID8394911 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8394911/
RECORD: Rec_0183332 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa bicolor [Animal]
-deltorphin-2
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Inhibition of ileum cells contraction Inhibition of vas deferens cells contraction Mu-receptor affinity Delta-receptor affinity Antinociceptive
PaperK. Richter et al. / PNAS 87 (1990) 4836-4839. cDNAs encoding [D-Ala2]deltorphin precursors from skin of Phyllomedusa bicolor also contain genetic information for three dermorphin-related opioid peptides Evidence URLhttps://www.uniprot.org/uniprotkb/P21850/entry
RECORD: Rec_0361021 VERIFIED: NO
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
8395
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Bio-Activity Profile
-
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