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MYP_079258
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Basic Information
Cy-AMP2 (Plant defensin)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
44 amino acids
C197H296N52O58S8
Standard
Sequence
KGGPCAKKPCCGPLGHYKVDCSTIPDYPCCSKYGFCGSGPQYCG
Physicochemical Analysis
4577.29 Da
8.47
2.76
2.38
0.0628
-0.39
0.36
0.05
9.60
26.59
0.1136
5960.00
6460.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1700.19
-20.24
64.0
70.0
137.0
315.0
12.0
44.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0317290 VERIFIED: YES
Provenance & Taxonomy
Cycas revoluta [Plant]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
multiple disulfide bonds reported, sites not specified
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-negative
Erwinia carotovora subsp. carotovora
8.1 μg/mL
IC50
PaperPubMed PMID 18778743 PMID18778743 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18778743/
RECORD: Rec_0364167 VERIFIED: YES
Provenance & Taxonomy
Cycas revoluta [Animal]
Defensin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Curtobacterium flaccumfaciens
8.3 μg/mL
IC50
PaperPubMed PMID: 18778743 PMID18778743 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18778743/
RECORD: Rec_0404065 VERIFIED: YES
Provenance & Taxonomy
Cycas revoluta [Animal]
Defensin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Agrobacterium rhizogenes
8.2 μg/mL
IC50
PaperPubMed PMID: 18778743 PMID18778743 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18778743/
RECORD: Rec_0411004 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0414701 VERIFIED: YES
Provenance & Taxonomy
Cycas revoluta [Animal]
Defensin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Geotrichum candidum
7 μg/mL
IC50
PaperPubMed PMID: 18778743 PMID18778743 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18778743/
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