Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length75 amino acids

Chemical FormulaC385H620N102O97S8

DescriptionStandard

        MKSLLFVLVVLVLLSCVPPVRSGPNIYIRRLFSTCWRTKGVCKTSCGKSEIHHIFCDSAHLCCIDKKYLPVEFGK
    

Molecular Weight8486.19 Da

Isoelectric Point (pI)9.28

Net Charge (pH 7.0)6.69

Net Charge (pH 7.4) 6.20

Charge Density (pH 7.0) 0.0892

GRAVY Index0.41

Hydrophobic Moment 0.80

Boman Index0.13

Instability Index65.02

Aliphatic Index 105.07

Aromaticity 0.0933

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3148.18

LogP -22.91

H-bond Donors 119.0

H-bond Acceptors 115.0

Rotatable Bonds 277.0

Heavy Atoms 592.0

Ring Count 15.0

Amide Bonds 75.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0029892 VERIFIED: NO

Provenance & Taxonomy

OrganismUrsus maritimus [Animal]

FamilyDefensin

Tax ID29073

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0347939 VERIFIED: NO