Peptide Database

Peptide NamePeptide Hp1090 (Non-disulfide-bridged peptide 4.9) (NDBP-4.9) (Non-disulfide-bridged peptide 5.9) (NDBP-5.9)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antiviral

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length68 amino acids

Chemical FormulaC355H548N82O105S3

DescriptionStandard

        MKTQFAIFLITLVLFQMFSQSDAIFKAIWSGIKSLFGKRGLSDLDDLDESFDGEVSQADIDFLKELMQ
    

Molecular Weight7740.83 Da

Isoelectric Point (pI)4.27

Net Charge (pH 7.0)-5.49

Net Charge (pH 7.4) -5.72

Charge Density (pH 7.0) -0.0807

GRAVY Index0.23

Hydrophobic Moment 0.63

Boman Index0.17

Instability Index16.18

Aliphatic Index 100.44

Aromaticity 0.1324

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3028.63

LogP -22.25

H-bond Donors 103.0

H-bond Acceptors 103.0

Rotatable Bonds 267.0

Heavy Atoms 545.0

Ring Count 10.0

Amide Bonds 72.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0219590 VERIFIED: YES

Provenance & Taxonomy

OrganismHeterometrus petersii [Animal]

FamilyNDBP

Structure & Mods

Confignon-disulfide-bridged amphipathic peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antiviral Anti-Gram-positive Cytolytic Toxin Non-hemolytic

TargetGram-positive bacteria