Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length440 amino acids

Chemical FormulaC2191H3476N590O621S9

DescriptionStandard

        TNPGFVVRITQAGLDYAHQQGIAILEKELARLKLPDISGDFRLLGKVHYQISDLDLRTFHLPHSRISLVPNVGLQVSISNAFAELNGNWRVKYGLIRSSGSFNLEVENIYIRIDLRLGSDSSGKPTIDTSSCSTRISKVRVHFSGKLSWLYNLFRKAIESRLRKALEGKVCDSVAKAVRNELQPYAQTLPVTARIDAMTGIDYALVAPPTTTALSLDTGLKGEFFSLANRSTVPFPPLPLDLPPDHDRMVYFGASSYFFNTAGFAYHSAGALVFEISDSMIPKGADFHLNTSTFSAFLPQLETKYPNLPMKFRLSTPSAPFLSIGPGGLSLQPMVDVQAYAVLPDTSLAPLFLLSLVTNVSAVMDVRSGNIVGSLTVGRIKFSLKQSDVGTFQVRTLQSVMNIVASKILLPRLNARLGQGFPLPLPDRIQLSNILVRFHQ
    

Molecular Weight48307.20 Da

Isoelectric Point (pI)9.58

Net Charge (pH 7.0)11.19

Net Charge (pH 7.4) 10.44

Charge Density (pH 7.0) 0.0254

GRAVY Index0.08

Hydrophobic Moment 0.77

Boman Index0.10

Instability Index36.61

Aliphatic Index 101.70

Aromaticity 0.0886

Extinction Coeff. Reduced 28880.00

Extinction Coeff. Oxidized 29005.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0248050 VERIFIED: NO

Provenance & Taxonomy

OrganismAlopecoenas beccarii [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria