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MYP_079165
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Basic Information
Warnericin RK (Bacteriocin)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
22 amino acids
C122H190N28O30S
Standard
Sequence
MQFITDLIKKAVDFFKGLFGNK
Physicochemical Analysis
2561.05 Da
9.52
1.50
1.28
0.0681
0.21
0.74
0.16
-15.21
88.64
0.1818
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
959.51
-4.59
32.0
33.0
89.0
181.0
4.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0311696 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Human erythrocytes
200 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/19804724/ PMID19804724 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19804724/
RECORD: Rec_0332402 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 50.0%, E 0.0%, T 27.3%, C 22.7% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Toxic Antimicrobial Hemolytic Cytotoxic Anti-Gram-negative
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0374541 VERIFIED: YES
Provenance & Taxonomy
Staphylococcus warneri [Bacterium]
Bacteriocin
Structure & Mods
branched peptide architecture [Branched]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Bacillus megaterium
12 μg/mL
MIC
PaperCharacterization of anti-Legionella activity of warnericin RK and delta-lysin I from Staphylococcus warneri.
RECORD: Rec_0389420 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0419154 VERIFIED: YES
Provenance & Taxonomy
Staphylococcus warneri [Bacterium]; Bacteria [Bacterium]
2; 2
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID17272268 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17272268/
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