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MYP_079165
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Basic Information
Warnericin RK (Bacteriocin)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
22 amino acids
C122H190N28O30S
Standard
Sequence
MQFITDLIKKAVDFFKGLFGNK
Physicochemical Analysis
2561.05 Da
9.52
1.50
1.28
0.0681
0.21
0.74
0.16
-15.21
88.64
0.1818
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
959.51
-4.59
32.0
33.0
89.0
181.0
4.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0158157 VERIFIED: YES
Provenance & Taxonomy
Staphylococcus warneri [Bacterium]
Bacteriocin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Gram-negative(Narrow)
PaperPubMed PMID: 18339450 | PubMed PMID: 19804724 PMID18339450;19804724 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18339450/
RECORD: Rec_0161105 VERIFIED: NO
Provenance & Taxonomy
Staphylococcus warneri [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Hemolytic
Legionella activity
RECORD: Rec_0174543 VERIFIED: YES
Provenance & Taxonomy
Staphylococcus epidermidis [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0177642 VERIFIED: YES
Provenance & Taxonomy
Staphylococcus warneri [Bacterium]
Bacteriocin
Structure & Mods
branched peptide architecture [Branched]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
In addition, MIC assays: L. pneumophila Lens
3 μg/mL
MIC
PaperCharacterization of anti-Legionella activity of warnericin RK and delta-lysin I from Staphylococcus warneri.
RECORD: Rec_0299843 VERIFIED: YES
Provenance & Taxonomy
Staphylococcus warneri RK [Bacterium]
Bacteriocin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PMID18339450 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18339450/
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