Peptide Database

Peptide NameUnnamed

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor

Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC185H303N53O52

DescriptionStandard

        TARLQLEARLQHLVAEILEREQSLALHALGYQLAFV
    

Molecular Weight4101.71 Da

Isoelectric Point (pI)5.98

Net Charge (pH 7.0)-1.42

Net Charge (pH 7.4) -1.72

Charge Density (pH 7.0) -0.0394

GRAVY Index0.27

Hydrophobic Moment 0.58

Boman Index0.10

Instability Index53.73

Aliphatic Index 141.11

Aromaticity 0.0556

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1707.13

LogP -12.30

H-bond Donors 59.0

H-bond Acceptors 53.0

Rotatable Bonds 139.0

Heavy Atoms 290.0

Ring Count 4.0

Amide Bonds 39.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0090180 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antiviral Antimicrobial

RECORD: Rec_0402280 VERIFIED: YES

Provenance & Taxonomy

OrganismHuman alphaherpesvirus 1 [Virus]

FamilyHeptad repeat peptide

Tax ID10298;0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Entry inhibitor Fusion inhibitor

TargetHerpes simplex virus 1 (Virus entry); Vero

Activity65 %

MethodPlaque assay

PaperAnalysis of synthetic peptides from heptad-repeat domains of herpes simplex virus type 1 glycoproteins H and B. | Galdiero S, Vitiello M, D'Isanto M, Falanga A, Collins C, Raieta K, Pedone C, Browne H, Galdiero M. | J Gen Virol. 2006 | PMID:16603508 PMID16603508 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16603508/