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MYP_079135
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
6 amino acids
C31H49N7O8
Standard
Sequence
YAKPVA
Physicochemical Analysis
647.76 Da
8.59
0.76
0.55
0.1263
0.17
0.48
0.20
67.33
81.67
0.1667
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
246.28
-0.90
8.0
9.0
17.0
46.0
2.0
5.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0156312 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
ACE
14.3 μM
IC50
RECORD: Rec_0233755 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
kappa-Casein-derived
9940
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
14.3 μM
IC50
PaperChanges in arterial blood pressure after single oral administration of milk-casein-derived peptides in spontaneously hypertensive rats | Miguel, M. et al. | DOI: 10.1002/mnfr.200900448 Evidence URLhttps://www.uniprot.org/uniprotkb/P02669/entry
RECORD: Rec_0265823 VERIFIED: NO
Provenance & Taxonomy
Ovis aries [Animal]
Casein-derived peptide
9940
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide Enzyme inhibitory
RECORD: Rec_0333037 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
14.3 μM
IC50
PaperAntihypertensive peptides: production, bioavailability and incorporation into foods. PMID21185549 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21185549/
RECORD: Rec_0342279 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
Spontaneously hypertensive rat (SHR)
23.1 mmHg
SBP decrease
PaperAntihypertensive peptides: production, bioavailability and incorporation into foods. PMID21185549 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21185549/
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