‹ ›
MYP_079113
← PREVIOUS NEXT → BACK
Basic Information
Beta-defensin 49 (Protein Defb49; rodents, mammals, animals)
Antimicrobial
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
84 amino acids
C436H728N122O111S11
Standard
Sequence
MKLPVLFLLFCFLDLLKTVKAEMKDTLFCFLKKGKCRHVCMNVEKRVGPCTKLNANCCIFVRDMRAIIPEDQRTVSIKIRNKQN
Physicochemical Analysis
9807.91 Da
9.63
9.52
9.13
0.1133
0.07
0.62
-0.05
26.16
97.38
0.0714
0.00
375.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3802.43
-28.38
138.0
133.0
340.0
680.0
10.0
90.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0081357 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Defensin
10116
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPubMed PMID: 16033865 PMID16033865 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16033865/
RECORD: Rec_0108799 VERIFIED: NO
Provenance & Taxonomy
Rattus norvegicus [Animal]
Defensin
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal
Qualitative functional evidence
PaperCross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract PMID16033865 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16033865/; https://www.uniprot.org/uniprotkb/Q32ZF1/entry; https://bblserver.org.in/ampdb/